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MBL Life Sciences
| Product Specifications | |
| Application | WB |
| Reactivity | Human |
| Clonality | Monoclonal IgG1 ĸ |
| Host | Mouse |
| Immunogen | Recombinant human full-length FLICE2 |
| Gene ID - Human | |
| Formulation | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Storage | -20C |
| Documents & Links for Anti-Caspase-10 (Human) mAb (Clone: 4C1) | |
| Datasheet | Anti-Caspase-10 (Human) mAb (Clone: 4C1) Datasheet |
| Documents & Links for Anti-Caspase-10 (Human) mAb (Clone: 4C1) | |
| Datasheet | Anti-Caspase-10 (Human) mAb (Clone: 4C1) Datasheet |
| Citations for Anti-Caspase-10 (Human) mAb (Clone: 4C1) – 15 Found |
| Kischkel, F C; Lawrence, D A; Tinel, A; LeBlanc, H; Virmani, A; Schow, P; Gazdar, A; Blenis, J; Arnott, D; Ashkenazi, A. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. The Journal Of Biological Chemistry. 2001;276(49):46639-46. PubMed - Comments: Used in: WB |
| Park, Soo-Jung; Wu, Ching-Haung; Gordon, John D; Zhong, Xiaoling; Emami, Armaghan; Safa, Ahmad R. Taxol induces caspase-10-dependent apoptosis. The Journal Of Biological Chemistry. 2004;279(49):51057-67. PubMed - Comments: Used in: WB |
| Koschny, Ronald; Holland, Heidrun; Sykora, Jaromir; Haas, Tobias L; Sprick, Martin R; Ganten, Tom M; Krupp, Wolfgang; Bauer, Manfred; Ahnert, Peter; Meixensberger, Jürgen; Walczak, Henning. Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research. 2007;13(11):3403-12. PubMed - Comments: Used in: WB |
| Hyer, Marc L; Shi, Ranxin; Krajewska, Maryla; Meyer, Colin; Lebedeva, Irina V; Fisher, Paul B; Reed, John C. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer. Cancer Research. 2008;68(8):2927-33. PubMed - Comments: Used in: WB |
| Verbrugge, I; de Vries, E; Tait, S W G; Wissink, E H J; Walczak, H; Verheij, M; Borst, J. Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway. Oncogene. 2008;27(5):574-84. PubMed - Comments: Used in: WB |
| Park, Soo-Jung; Wu, Ching-Haung; Gordon, John D; Zhong, Xiaoling; Emami, Armaghan; Safa, Ahmad R. Taxol induces caspase-10-dependent apoptosis. The Journal Of Biological Chemistry. 2004;279(49):51057-67. PubMed - Comments: Used in: WB |
| Lafont, Elodie; Milhas, Delphine; Teissié, Justin; Therville, Nicole; Andrieu-Abadie, Nathalie; Levade, Thierry; Benoist, Hervé; Ségui, Bruno. Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk. Plos One. 2010;5(10):e13638. PubMed - Comments: Used in: WB |
| Cazanave, Sophie C; Mott, Justin L; Bronk, Steven F; Werneburg, Nathan W; Fingas, Christian D; Meng, X Wei; Finnberg, Niklas; El-Deiry, Wafik S; Kaufmann, Scott H; Gores, Gregory J. Death receptor 5 signaling promotes hepatocyte lipoapoptosis. The Journal Of Biological Chemistry. 2011;286(45):39336-48. PubMed - Comments: Used in: WB |
| Estornes, Y; Toscano, F; Virard, F; Jacquemin, G; Pierrot, A; Vanbervliet, B; Bonnin, M; Lalaoui, N; Mercier-Gouy, P; Pachéco, Y; Salaun, B; Renno, T; Micheau, O; Lebecque, S. dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death And Differentiation. 2012;19(9):1482-94. PubMed - Comments: Used in: WB |
| Schleich, K; Buchbinder, J H; Pietkiewicz, S; Kähne, T; Warnken, U; Öztürk, S; Schnölzer, M; Naumann, M; Krammer, P H; Lavrik, I N. Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain. Cell Death And Differentiation. 2016;23(4):681-94. PubMed - Comments: Used in: WB |
| Visiedo, Francisco; Santos-Rosendo, Celeste; Mateos-Bernal, Rosa M; Gil-Sánchez, M Del Mar; Bugatto, Fernando; Aguilar-Diosdado, Manuel; Segundo, Carmen; López-Tinoco, Cristina. Characterization of NO-Induced Nitrosative Status in Human Placenta from Pregnant Women with Gestational Diabetes Mellitus. Oxidative Medicine And Cellular Longevity. 2017:5629341. PubMed - Comments: Used in: WB |
| Pešková, Lucie; Vinarský, Vladimír; Bárta, Tomáš; Hampl, Aleš. Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin. Stem Cells International. 2019:4279481. PubMed - Comments: Used in: WB |
| Kumari, Rajni; Deshmukh, Ruhi S; Das, Sanjeev. Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis. Nature Communications. 2019;10(1):4255. PubMed - Comments: Used in: WB |
| Lee, So-Ra; Quan, Khong Trong; Byun, Hee Sun; Park, InWha; Kang, Kidong; Piao, Xuezhe; Ju, Eunjin; Ro, Hyunju; Na, MinKyun; Hur, Gang Min. Accelerated degradation of cFLIP(L) and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Scientific Reports. 2019;9(1):13505. PubMed - Comments: Used in: WB |
| Elmallah, Mohammed I Y; Cogo, Sheron; Constantinescu, Andrei A; Elifio-Esposito, Selene; Abdelfattah, Mohammed S; Micheau, Olivier. Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP. Cells. 2020;9(8) PubMed - Comments: Used in: WB |
No reviews have been added for this product.
MBL Life Sciences
| Product Specifications | |
| Application | WB |
| Reactivity | Human |
| Clonality | Monoclonal IgG1 ĸ |
| Host | Mouse |
| Immunogen | Recombinant human full-length FLICE2 |
| Gene ID - Human | |
| Formulation | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Storage | -20C |
| Documents & Links for Anti-Caspase-10 (Human) mAb (Clone: 4C1) | |
| Datasheet | Anti-Caspase-10 (Human) mAb (Clone: 4C1) Datasheet |
| Documents & Links for Anti-Caspase-10 (Human) mAb (Clone: 4C1) | |
| Datasheet | Anti-Caspase-10 (Human) mAb (Clone: 4C1) Datasheet |
| Citations for Anti-Caspase-10 (Human) mAb (Clone: 4C1) – 15 Found |
| Kischkel, F C; Lawrence, D A; Tinel, A; LeBlanc, H; Virmani, A; Schow, P; Gazdar, A; Blenis, J; Arnott, D; Ashkenazi, A. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. The Journal Of Biological Chemistry. 2001;276(49):46639-46. PubMed - Comments: Used in: WB |
| Park, Soo-Jung; Wu, Ching-Haung; Gordon, John D; Zhong, Xiaoling; Emami, Armaghan; Safa, Ahmad R. Taxol induces caspase-10-dependent apoptosis. The Journal Of Biological Chemistry. 2004;279(49):51057-67. PubMed - Comments: Used in: WB |
| Koschny, Ronald; Holland, Heidrun; Sykora, Jaromir; Haas, Tobias L; Sprick, Martin R; Ganten, Tom M; Krupp, Wolfgang; Bauer, Manfred; Ahnert, Peter; Meixensberger, Jürgen; Walczak, Henning. Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research. 2007;13(11):3403-12. PubMed - Comments: Used in: WB |
| Hyer, Marc L; Shi, Ranxin; Krajewska, Maryla; Meyer, Colin; Lebedeva, Irina V; Fisher, Paul B; Reed, John C. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer. Cancer Research. 2008;68(8):2927-33. PubMed - Comments: Used in: WB |
| Verbrugge, I; de Vries, E; Tait, S W G; Wissink, E H J; Walczak, H; Verheij, M; Borst, J. Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway. Oncogene. 2008;27(5):574-84. PubMed - Comments: Used in: WB |
| Park, Soo-Jung; Wu, Ching-Haung; Gordon, John D; Zhong, Xiaoling; Emami, Armaghan; Safa, Ahmad R. Taxol induces caspase-10-dependent apoptosis. The Journal Of Biological Chemistry. 2004;279(49):51057-67. PubMed - Comments: Used in: WB |
| Lafont, Elodie; Milhas, Delphine; Teissié, Justin; Therville, Nicole; Andrieu-Abadie, Nathalie; Levade, Thierry; Benoist, Hervé; Ségui, Bruno. Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk. Plos One. 2010;5(10):e13638. PubMed - Comments: Used in: WB |
| Cazanave, Sophie C; Mott, Justin L; Bronk, Steven F; Werneburg, Nathan W; Fingas, Christian D; Meng, X Wei; Finnberg, Niklas; El-Deiry, Wafik S; Kaufmann, Scott H; Gores, Gregory J. Death receptor 5 signaling promotes hepatocyte lipoapoptosis. The Journal Of Biological Chemistry. 2011;286(45):39336-48. PubMed - Comments: Used in: WB |
| Estornes, Y; Toscano, F; Virard, F; Jacquemin, G; Pierrot, A; Vanbervliet, B; Bonnin, M; Lalaoui, N; Mercier-Gouy, P; Pachéco, Y; Salaun, B; Renno, T; Micheau, O; Lebecque, S. dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death And Differentiation. 2012;19(9):1482-94. PubMed - Comments: Used in: WB |
| Schleich, K; Buchbinder, J H; Pietkiewicz, S; Kähne, T; Warnken, U; Öztürk, S; Schnölzer, M; Naumann, M; Krammer, P H; Lavrik, I N. Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain. Cell Death And Differentiation. 2016;23(4):681-94. PubMed - Comments: Used in: WB |
| Visiedo, Francisco; Santos-Rosendo, Celeste; Mateos-Bernal, Rosa M; Gil-Sánchez, M Del Mar; Bugatto, Fernando; Aguilar-Diosdado, Manuel; Segundo, Carmen; López-Tinoco, Cristina. Characterization of NO-Induced Nitrosative Status in Human Placenta from Pregnant Women with Gestational Diabetes Mellitus. Oxidative Medicine And Cellular Longevity. 2017:5629341. PubMed - Comments: Used in: WB |
| Pešková, Lucie; Vinarský, Vladimír; Bárta, Tomáš; Hampl, Aleš. Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin. Stem Cells International. 2019:4279481. PubMed - Comments: Used in: WB |
| Kumari, Rajni; Deshmukh, Ruhi S; Das, Sanjeev. Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis. Nature Communications. 2019;10(1):4255. PubMed - Comments: Used in: WB |
| Lee, So-Ra; Quan, Khong Trong; Byun, Hee Sun; Park, InWha; Kang, Kidong; Piao, Xuezhe; Ju, Eunjin; Ro, Hyunju; Na, MinKyun; Hur, Gang Min. Accelerated degradation of cFLIP(L) and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Scientific Reports. 2019;9(1):13505. PubMed - Comments: Used in: WB |
| Elmallah, Mohammed I Y; Cogo, Sheron; Constantinescu, Andrei A; Elifio-Esposito, Selene; Abdelfattah, Mohammed S; Micheau, Olivier. Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP. Cells. 2020;9(8) PubMed - Comments: Used in: WB |
