Product Description

EpCAM (epithelial cell adhesion molecule) is a glycoprotein that facilitates homo-typical adhesion of cells, and highly overexpressed in multiple types of carcinomas, has been found in pseudo-stratified, transitional and simple epithelia on the basolateral surfaces and has been identified as a cargo protein in exosomes. MicroRNA profiling of circulating tumor exosomes collected by anti EpCAM antibody could potentially be used as surrogate diagnostic markers for biopsy profiling, extending its utility to screening asymptomatic populations. Recent discoveries of the presence of microRNAs, EpCAM and CD24 in ovarian tumor-derived exosomes have been highly promising alternatives for early detection of ovarian cancer