A cytosolic surveillance system mediated by the nucleotide-binding oligomerization domain (NOD) proteins plays an important role in recognizing intracellular microbe-associated molecular patterns (MAMPs). It has been found that

meso-diaminopimelic acid (meso-DAP)-containing peptide moieties, such as γ-D-glutamyl-meso-DAP (iE-DAP) are recognized by NOD1. Porcine NOD1 is more closely related to the human protein than the mouse counterpart and that it is expressed not only in the cytoplasm but also on the inner side of the plasma membrane in the transfected cells. This antibody is useful for biochemical and immunohistochemical analyzes of porcine NOD1 and for clarifying how the

immune system is modulated by low-molecular weight peptidoglycan fragments through NOD1.

Product type]: Primary antibody

Immunogen]: Amino acids 404-416 of porcine NOD1

Rased in]: Rabbit

Cross reactivity]:

Reacts with porcine. Not yet tested in other species

Application notes Recommended dilutions: ・ Immunohistochemistry: 1/25-1/500

・ Flow cytometry: 1/50-1/500

・ Western blotting: 1/25-1/500

Other applications have not been tested.

Optimal dilutions/concentrations should be determined by the end user.

A cytosolic surveillance system mediated by the nucleotide-binding oligomerization domain (NOD) proteins plays an important role in recognizing intracellular microbe-associated molecular patterns (MAMPs). It has been found that

meso-diaminopimelic acid (meso-DAP)-containing peptide moieties, such as γ-D-glutamyl-meso-DAP (iE-DAP) are recognized by NOD1. Porcine NOD1 is more closely related to the human protein than the mouse counterpart and that it is expressed not only in the cytoplasm but also on the inner side of the plasma membrane in the transfected cells. This antibody is useful for biochemical and immunohistochemical analyzes of porcine NOD1 and for clarifying how the

immune system is modulated by low-molecular weight peptidoglycan fragments through NOD1.

Product type]: Primary antibody

Immunogen]: Amino acids 404-416 of porcine NOD1

Rased in]: Rabbit

Cross reactivity]:

Reacts with porcine. Not yet tested in other species

Application notes Recommended dilutions: ・ Immunohistochemistry: 1/25-1/500

・ Flow cytometry: 1/50-1/500

・ Western blotting: 1/25-1/500

Other applications have not been tested.

Optimal dilutions/concentrations should be determined by the end user.