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MBL Life Sciences
MBL Life Sciences
| Product Specifications | |
| Formulation | 100 mM Z-VAD-FMK in DMSO |
| Storage | -20C |
| Documents & Links for Caspase inhibitor Z-VAD-FMK | |
| Datasheet | Caspase inhibitor Z-VAD-FMK Datasheet |
| Documents & Links for Caspase inhibitor Z-VAD-FMK | |
| Datasheet | Caspase inhibitor Z-VAD-FMK Datasheet |
| Citations for Caspase inhibitor Z-VAD-FMK – 20 Found |
| Ito, Tetsuro; Akao, Yukihiro; Yi, Hong; Ohguchi, Kenji; Matsumoto, Kenji; Tanaka, Toshiyuki; Iinuma, Munekazu; Nozawa, Yoshinori. Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C. Carcinogenesis. 2003;24(9):1489-97. PubMed |
| Kobayashi, Shinya; Kajino, Shinichi; Takahashi, Naoko; Kanazawa, Satoshi; Imai, Kenichi; Hibi, Yurina; Ohara, Hirotaka; Itoh, Makoto; Okamoto, Takashi. 53BP2 induces apoptosis through the mitochondrial death pathway. Genes To Cells : Devoted To Molecular & Cellular Mechanisms. 2005;10(3):253-60. PubMed |
| Matsumoto, T; Hosono-Nishiyama, K; Yamada, H. Antiproliferative and apoptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells. Planta Medica. 2006;72(3):276-8. PubMed |
| Nakagawa, Yoshihito; Iinuma, Munekazu; Naoe, Tomoki; Nozawa, Yoshinori; Akao, Yukihiro. Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorganic & Medicinal Chemistry. 2007;15(16):5620-8. PubMed |
| Yuan, Guohua; Zhang, Li; Yang, Guobin; Yang, Jingwen; Wan, Chunyan; Zhang, Lu; Song, Guangtai; Chen, Shuo; Chen, Zhi. The distribution and ultrastructure of the forming blood capillaries and the effect of apoptosis on vascularization in mouse embryonic molar mesenchyme. Cell And Tissue Research. 2014;356(1):137-45. PubMed |
| Kozako, Tomohiro; Suzuki, Takayoshi; Yoshimitsu, Makoto; Uchida, Yuichiro; Kuroki, Ayako; Aikawa, Akiyoshi; Honda, Shin-ichiro; Arima, Naomichi; Soeda, Shinji. Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells. Scientific Reports. 2015;5:11345. PubMed |
| Wang, Chunli; Ye, Mingliang; Wei, Xiaoluan; Bian, Yangyang; Cheng, Kai; Zou, Hanfa. A bead-based cleavage method for large-scale identification of protease substrates. Scientific Reports. 2016;6:22645. PubMed |
| Wang, Chunli; Ye, Mingliang; Wei, Xiaoluan; Bian, Yangyang; Cheng, Kai; Zou, Hanfa. A bead-based cleavage method for large-scale identification of protease substrates. Scientific Reports. 2016;6:22645. PubMed |
| Kitazawa, Masato; Hida, Shigeaki; Fujii, Chifumi; Taniguchi, Shun'ichiro; Ito, Kensuke; Matsumura, Tomio; Okada, Nagisa; Sakaizawa, Takashi; Kobayashi, Akira; Takeoka, Michiko; Miyagawa, Shin-Ichi. ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication. Plos One. 12(1):e0169340. PubMed |
| Tokunaga, Etsuko; Akiyama, Hidehiko; Soloshonok, Vadim A; Inoue, Yuki; Hara, Hideaki; Shibata, Norio. Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. Plos One. 12(8):e0182152. PubMed |
| Hsu, Jung-Mao; Xia, Weiya; Hsu, Yi-Hsin; Chan, Li-Chuan; Yu, Wen-Hsuan; Cha, Jong-Ho; Chen, Chun-Te; Liao, Hsin-Wei; Kuo, Chu-Wei; Khoo, Kay-Hooi; Hsu, Jennifer L; Li, Chia-Wei; Lim, Seung-Oe; Chang, Shih-Shin; Chen, Yi-Chun; Ren, Guo-Xin; Hung, Mien-Chie. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nature Communications. 2018;9(1):1908. PubMed |
| Kozako, Tomohiro; Sato, Keisuke; Uchida, Yuichiro; Kato, Naho; Aikawa, Akiyoshi; Ogata, Kentaro; Kamimura, Hidetoshi; Uemura, Haruna; Yoshimitsu, Makoto; Ishitsuka, Kenji; Higaki, Yasuki; Tanaka, Hiroaki; Honda, Shin-Ichiro; Soeda, Shinji. The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells. Oncotarget. 2018;9(45):27645-27655. PubMed |
| Kozako, Tomohiro; Mellini, Paolo; Ohsugi, Takeo; Aikawa, Akiyoshi; Uchida, Yu-Ichiro; Honda, Shin-Ichiro; Suzuki, Takayoshi. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. Bmc Cancer. 2018;18(1):791. PubMed |
| Hirasawa, Masaaki; Kurita-Ochiai, Tomoko. Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells. Mediators Of Inflammation. 2018:1967506. PubMed |
| Zhang, Enxiang; Lu, Xiaotong; Yin, Shutao; Yan, Mingzhu; Lu, Shangyun; Fan, Lihong; Hu, Hongbo. The functional role of Bax/Bak in palmitate-induced lipoapoptosis. Food And Chemical Toxicology : An International Journal Published For The British Industrial Biological Research Association. 2019;123:268-274. PubMed |
| Hoshi, Taisuke; Watanabe Miyano, Saori; Watanabe, Hideki; Sonobe, Regina Mikie Kanada; Seki, Yuki; Ohta, Etsuko; Nomoto, Kenichi; Matsui, Junji; Funahashi, Yasuhiro. Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR-MAPK cascades. Biochemical And Biophysical Research Communications. 2019;513(1):1-7. PubMed - Comments: Used in: Function |
| Sanjo, Hideki; Nakayama, Jun; Yoshizawa, Takahiro; Fehling, Hans Joerg; Akira, Shizuo; Taki, Shinsuke. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. Journal Of Immunology (Baltimore, Md. : 1950). 2019;203(4):783-788. PubMed |
| Matsuo, Kentaro; Taniguchi, Kohei; Hamamoto, Hiroki; Ito, Yuko; Futaki, Sugiko; Inomata, Yosuke; Shima, Takafumi; Asakuma, Mitsuhiro; Lee, Sang-Woong; Tanaka, Keitaro; Okuda, Junji; Kondo, Yoichi; Uchiyama, Kazuhisa. Delta-like 3 localizes to neuroendocrine cells and plays a pivotal role in gastrointestinal neuroendocrine malignancy. Cancer Science. 2019;110(10):3122-3131. PubMed |
| Sasaki, Katsuhiro; Himeno, Ai; Nakagawa, Tomoko; Sasaki, Yoshiteru; Kiyonari, Hiroshi; Iwai, Kazuhiro. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nature Communications. 2019;10(1):3878. PubMed |
| Aoki, Kana; Satoi, Shinsuke; Harada, Shota; Uchida, Seiichi; Iwasa, Yoh; Ikenouchi, Junichi. Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb. Molecular Biology Of The Cell. 2020;31(8):833-844. PubMed - Comments: Used in: Function |
| Product Specifications | |
| Formulation | 100 mM Z-VAD-FMK in DMSO |
| Storage | -20C |
| Documents & Links for Caspase inhibitor Z-VAD-FMK | |
| Datasheet | Caspase inhibitor Z-VAD-FMK Datasheet |
| Documents & Links for Caspase inhibitor Z-VAD-FMK | |
| Datasheet | Caspase inhibitor Z-VAD-FMK Datasheet |
| Citations for Caspase inhibitor Z-VAD-FMK – 20 Found |
| Ito, Tetsuro; Akao, Yukihiro; Yi, Hong; Ohguchi, Kenji; Matsumoto, Kenji; Tanaka, Toshiyuki; Iinuma, Munekazu; Nozawa, Yoshinori. Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C. Carcinogenesis. 2003;24(9):1489-97. PubMed |
| Kobayashi, Shinya; Kajino, Shinichi; Takahashi, Naoko; Kanazawa, Satoshi; Imai, Kenichi; Hibi, Yurina; Ohara, Hirotaka; Itoh, Makoto; Okamoto, Takashi. 53BP2 induces apoptosis through the mitochondrial death pathway. Genes To Cells : Devoted To Molecular & Cellular Mechanisms. 2005;10(3):253-60. PubMed |
| Matsumoto, T; Hosono-Nishiyama, K; Yamada, H. Antiproliferative and apoptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells. Planta Medica. 2006;72(3):276-8. PubMed |
| Nakagawa, Yoshihito; Iinuma, Munekazu; Naoe, Tomoki; Nozawa, Yoshinori; Akao, Yukihiro. Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorganic & Medicinal Chemistry. 2007;15(16):5620-8. PubMed |
| Yuan, Guohua; Zhang, Li; Yang, Guobin; Yang, Jingwen; Wan, Chunyan; Zhang, Lu; Song, Guangtai; Chen, Shuo; Chen, Zhi. The distribution and ultrastructure of the forming blood capillaries and the effect of apoptosis on vascularization in mouse embryonic molar mesenchyme. Cell And Tissue Research. 2014;356(1):137-45. PubMed |
| Kozako, Tomohiro; Suzuki, Takayoshi; Yoshimitsu, Makoto; Uchida, Yuichiro; Kuroki, Ayako; Aikawa, Akiyoshi; Honda, Shin-ichiro; Arima, Naomichi; Soeda, Shinji. Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells. Scientific Reports. 2015;5:11345. PubMed |
| Wang, Chunli; Ye, Mingliang; Wei, Xiaoluan; Bian, Yangyang; Cheng, Kai; Zou, Hanfa. A bead-based cleavage method for large-scale identification of protease substrates. Scientific Reports. 2016;6:22645. PubMed |
| Wang, Chunli; Ye, Mingliang; Wei, Xiaoluan; Bian, Yangyang; Cheng, Kai; Zou, Hanfa. A bead-based cleavage method for large-scale identification of protease substrates. Scientific Reports. 2016;6:22645. PubMed |
| Kitazawa, Masato; Hida, Shigeaki; Fujii, Chifumi; Taniguchi, Shun'ichiro; Ito, Kensuke; Matsumura, Tomio; Okada, Nagisa; Sakaizawa, Takashi; Kobayashi, Akira; Takeoka, Michiko; Miyagawa, Shin-Ichi. ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication. Plos One. 12(1):e0169340. PubMed |
| Tokunaga, Etsuko; Akiyama, Hidehiko; Soloshonok, Vadim A; Inoue, Yuki; Hara, Hideaki; Shibata, Norio. Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. Plos One. 12(8):e0182152. PubMed |
| Hsu, Jung-Mao; Xia, Weiya; Hsu, Yi-Hsin; Chan, Li-Chuan; Yu, Wen-Hsuan; Cha, Jong-Ho; Chen, Chun-Te; Liao, Hsin-Wei; Kuo, Chu-Wei; Khoo, Kay-Hooi; Hsu, Jennifer L; Li, Chia-Wei; Lim, Seung-Oe; Chang, Shih-Shin; Chen, Yi-Chun; Ren, Guo-Xin; Hung, Mien-Chie. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nature Communications. 2018;9(1):1908. PubMed |
| Kozako, Tomohiro; Sato, Keisuke; Uchida, Yuichiro; Kato, Naho; Aikawa, Akiyoshi; Ogata, Kentaro; Kamimura, Hidetoshi; Uemura, Haruna; Yoshimitsu, Makoto; Ishitsuka, Kenji; Higaki, Yasuki; Tanaka, Hiroaki; Honda, Shin-Ichiro; Soeda, Shinji. The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells. Oncotarget. 2018;9(45):27645-27655. PubMed |
| Kozako, Tomohiro; Mellini, Paolo; Ohsugi, Takeo; Aikawa, Akiyoshi; Uchida, Yu-Ichiro; Honda, Shin-Ichiro; Suzuki, Takayoshi. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. Bmc Cancer. 2018;18(1):791. PubMed |
| Hirasawa, Masaaki; Kurita-Ochiai, Tomoko. Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells. Mediators Of Inflammation. 2018:1967506. PubMed |
| Zhang, Enxiang; Lu, Xiaotong; Yin, Shutao; Yan, Mingzhu; Lu, Shangyun; Fan, Lihong; Hu, Hongbo. The functional role of Bax/Bak in palmitate-induced lipoapoptosis. Food And Chemical Toxicology : An International Journal Published For The British Industrial Biological Research Association. 2019;123:268-274. PubMed |
| Hoshi, Taisuke; Watanabe Miyano, Saori; Watanabe, Hideki; Sonobe, Regina Mikie Kanada; Seki, Yuki; Ohta, Etsuko; Nomoto, Kenichi; Matsui, Junji; Funahashi, Yasuhiro. Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR-MAPK cascades. Biochemical And Biophysical Research Communications. 2019;513(1):1-7. PubMed - Comments: Used in: Function |
| Sanjo, Hideki; Nakayama, Jun; Yoshizawa, Takahiro; Fehling, Hans Joerg; Akira, Shizuo; Taki, Shinsuke. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. Journal Of Immunology (Baltimore, Md. : 1950). 2019;203(4):783-788. PubMed |
| Matsuo, Kentaro; Taniguchi, Kohei; Hamamoto, Hiroki; Ito, Yuko; Futaki, Sugiko; Inomata, Yosuke; Shima, Takafumi; Asakuma, Mitsuhiro; Lee, Sang-Woong; Tanaka, Keitaro; Okuda, Junji; Kondo, Yoichi; Uchiyama, Kazuhisa. Delta-like 3 localizes to neuroendocrine cells and plays a pivotal role in gastrointestinal neuroendocrine malignancy. Cancer Science. 2019;110(10):3122-3131. PubMed |
| Sasaki, Katsuhiro; Himeno, Ai; Nakagawa, Tomoko; Sasaki, Yoshiteru; Kiyonari, Hiroshi; Iwai, Kazuhiro. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nature Communications. 2019;10(1):3878. PubMed |
| Aoki, Kana; Satoi, Shinsuke; Harada, Shota; Uchida, Seiichi; Iwasa, Yoh; Ikenouchi, Junichi. Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb. Molecular Biology Of The Cell. 2020;31(8):833-844. PubMed - Comments: Used in: Function |