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MBL Life Sciences
| Product Specifications | |
| Application | ELISA |
| Sensitivity | better than 38.1 pg/ml of sample. |
| Documents & Links for CircuLex Mouse/Rat PCSK9 ELISA Kit | |
| Datasheet | CircuLex Mouse/Rat PCSK9 ELISA Kit Datasheet |
| Documents & Links for CircuLex Mouse/Rat PCSK9 ELISA Kit | |
| Datasheet | CircuLex Mouse/Rat PCSK9 ELISA Kit Datasheet |
| Citations for CircuLex Mouse/Rat PCSK9 ELISA Kit – 22 Found |
| Chen, Xiao-Wei; Wang, He; Bajaj, Kanika; Zhang, Pengcheng; Meng, Zhuo-Xian; Ma, Danjun; Bai, Yongsheng; Liu, Hui-Hui; Adams, Elizabeth; Baines, Andrea; Yu, Genggeng; Sartor, Maureen A; Zhang, Bin; Yi, Zhengping; Lin, Jiandie; Young, Stephen G; Schekman, Randy; Ginsburg, David. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife. 2013;2:e00444. PubMed |
| Carrier, Bradley; Wen, Shin; Zigouras, Sophia; Browne, Richard W; Li, Zhuyun; Patel, Mulchand S; Williamson, David L; Rideout, Todd C. Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats. Plos One. 9(3):e90863. PubMed |
| Sasaki, Makoto; Terao, Yoshio; Ayaori, Makoto; Uto-Kondo, Harumi; Iizuka, Maki; Yogo, Makiko; Hagisawa, Kosuke; Takiguchi, Shunichi; Yakushiji, Emi; Nakaya, Kazuhiro; Ogura, Masatsune; Komatsu, Tomohiro; Ikewaki, Katsunori. Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways. Arteriosclerosis, Thrombosis, And Vascular Biology. 2014;34(6):1171-8. PubMed |
| Galabova, Gergana; Brunner, Sylvia; Winsauer, Gabriele; Juno, Claudia; Wanko, Bettina; Mairhofer, Andreas; Lührs, Petra; Schneeberger, Achim; von Bonin, Arne; Mattner, Frank; Schmidt, Walter; Staffler, Guenther. Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management. Plos One. 9(12):e114469. PubMed |
| Berger, Jean-Mathieu; Vaillant, Nathalie; Le May, Cédric; Calderon, Carolina; Brégeon, Jeremy; Prieur, Xavier; Hadchouel, Juliette; Loirand, Gervaise; Cariou, Bertrand. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. Atherosclerosis. 2015;239(1):252-9. PubMed |
| Butkinaree, Chutikarn; Canuel, Maryssa; Essalmani, Rachid; Poirier, Steve; Benjannet, Suzanne; Asselin, Marie-Claude; Roubtsova, Anna; Hamelin, Josée; Marcinkiewicz, Jadwiga; Chamberland, Ann; Guillemot, Johann; Mayer, Gaétan; Sisodia, Sangram S; Jacob, Yves; Prat, Annik; Seidah, Nabil G. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. The Journal Of Biological Chemistry. 2015;290(30):18609-20. PubMed |
| An, Dong; Wei, Xiaowei; Li, Hui; Gu, Hui; Huang, Tianchu; Zhao, Guifeng; Liu, Bo; Wang, Weilin; Chen, Lizhu; Ma, Wei; Zhang, Henan; Cao, Songying; Yuan, Zhengwei. Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. Scientific Reports. 2015;5:17559. PubMed |
| Haas, Mary E; Levenson, Amy E; Sun, Xiaowei; Liao, Wan-Hui; Rutkowski, Joseph M; de Ferranti, Sarah D; Schumacher, Valerie A; Scherer, Philipp E; Salant, David J; Biddinger, Sudha B. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation. 2016;134(1):61-72. PubMed |
| Ngo Sock, Emilienne Tudor; Mayer, Gaétan; Lavoie, Jean-Marc. Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats. Plos One. 11(7):e0159550. PubMed |
| Lintner, Nathanael G; McClure, Kim F; Petersen, Donna; Londregan, Allyn T; Piotrowski, David W; Wei, Liuqing; Xiao, Jun; Bolt, Michael; Loria, Paula M; Maguire, Bruce; Geoghegan, Kieran F; Huang, Austin; Rolph, Tim; Liras, Spiros; Doudna, Jennifer A; Dullea, Robert G; Cate, Jamie H D. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. Plos Biology. 2017;15(3):e2001882. PubMed |
| Xu, Yu-Xin; Redon, Valeska; Yu, Haojie; Querbes, William; Pirruccello, James; Liebow, Abigail; Deik, Amy; Trindade, Kevin; Wang, Xiao; Musunuru, Kiran; Clish, Clary B; Cowan, Chad; Fizgerald, Kevin; Rader, Daniel; Kathiresan, Sekar. Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis. 2018;268:196-206. PubMed |
| Yang, Sheng-Hua; Xu, Rui-Xia; Cui, Chuan-Jue; Wang, Yin; Du, Ying; Chen, Zhi-Guo; Yao, Yu-Hong; Ma, Chun-Yan; Zhu, Cheng-Gang; Guo, Yuan-Lin; Wu, Na-Qiong; Sun, Jing; Chen, Bu-Xing; Li, Jian-Jun. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovascular Diabetology. 2018;17(1):48. PubMed |
| Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Shahanawaz, Jiwani; Theus, Sue; Fan, Yubo; Deng, Xiaoyan; Zhou, Sichang; Mehta, Jawahar L. PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy. Cardiovascular Research. 2018;114(13):1738-1751. PubMed |
| Liu, Yan; Wang, Xiaona; Han, Jie; Liu, Lu; Jin, Ying; Jin, Liyuan; Ye, Ping. PCSK9 positively correlates with plasma sdLDL in community-dwelling population but not in diabetic participants after confounder adjustment. Medicine. 2019;98(14):e15062. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer. Archives Of Medical Science : Ams. 2019;15(3):559-569. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunization against PCSK9 in an experimental model of breast cancer. Archives Of Medical Science : Ams. 2019;15(3):570-579. PubMed |
| Momtazi-Borojeni, Amir Abbas; Jaafari, Mahmoud Reza; Badiee, Ali; Banach, Maciej; Sahebkar, Amirhossein. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. Bmc Medicine. 2019;17(1):223. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunisation against PCSK9 in mice bearing melanoma. Archives Of Medical Science : Ams. 16(1):189-199. PubMed |
| Low, Lauretta D; Lu, Liangjian; Chan, Chang-Yien; Chen, Jinmiao; Yang, Henry H; Yu, Hanry; Lee, Caroline G L; Ng, Kar-Hui; Yap, Hui-Kim. IL-13-driven alterations in hepatic cholesterol handling contributes to hypercholesterolemia in a rat model of minimal change disease. Clinical Science (London, England : 1979). 2020;134(2):225-237. PubMed |
| Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344. PubMed |
| St-Amand, Roxane; Ngo Sock, Émilienne T; Quinn, Samantha; Lavoie, Jean-Marc; St-Pierre, David H. Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats. Lipids In Health And Disease. 2020;19(1):192. PubMed |
| Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Zhou, Sichang; Kore, Rajshekhar A; Mu, Shengyu; Deng, Xiaoyan; Fan, Yubo; Mehta, Jawahar L. NLRP3 inflammasome via IL-1β regulates PCSK9 secretion. Theranostics. 10(16):7100-7110. PubMed |
MBL Life Sciences
| Product Specifications | |
| Application | ELISA |
| Sensitivity | better than 38.1 pg/ml of sample. |
| Documents & Links for CircuLex Mouse/Rat PCSK9 ELISA Kit | |
| Datasheet | CircuLex Mouse/Rat PCSK9 ELISA Kit Datasheet |
| Documents & Links for CircuLex Mouse/Rat PCSK9 ELISA Kit | |
| Datasheet | CircuLex Mouse/Rat PCSK9 ELISA Kit Datasheet |
| Citations for CircuLex Mouse/Rat PCSK9 ELISA Kit – 22 Found |
| Chen, Xiao-Wei; Wang, He; Bajaj, Kanika; Zhang, Pengcheng; Meng, Zhuo-Xian; Ma, Danjun; Bai, Yongsheng; Liu, Hui-Hui; Adams, Elizabeth; Baines, Andrea; Yu, Genggeng; Sartor, Maureen A; Zhang, Bin; Yi, Zhengping; Lin, Jiandie; Young, Stephen G; Schekman, Randy; Ginsburg, David. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife. 2013;2:e00444. PubMed |
| Carrier, Bradley; Wen, Shin; Zigouras, Sophia; Browne, Richard W; Li, Zhuyun; Patel, Mulchand S; Williamson, David L; Rideout, Todd C. Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats. Plos One. 9(3):e90863. PubMed |
| Sasaki, Makoto; Terao, Yoshio; Ayaori, Makoto; Uto-Kondo, Harumi; Iizuka, Maki; Yogo, Makiko; Hagisawa, Kosuke; Takiguchi, Shunichi; Yakushiji, Emi; Nakaya, Kazuhiro; Ogura, Masatsune; Komatsu, Tomohiro; Ikewaki, Katsunori. Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways. Arteriosclerosis, Thrombosis, And Vascular Biology. 2014;34(6):1171-8. PubMed |
| Galabova, Gergana; Brunner, Sylvia; Winsauer, Gabriele; Juno, Claudia; Wanko, Bettina; Mairhofer, Andreas; Lührs, Petra; Schneeberger, Achim; von Bonin, Arne; Mattner, Frank; Schmidt, Walter; Staffler, Guenther. Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management. Plos One. 9(12):e114469. PubMed |
| Berger, Jean-Mathieu; Vaillant, Nathalie; Le May, Cédric; Calderon, Carolina; Brégeon, Jeremy; Prieur, Xavier; Hadchouel, Juliette; Loirand, Gervaise; Cariou, Bertrand. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. Atherosclerosis. 2015;239(1):252-9. PubMed |
| Butkinaree, Chutikarn; Canuel, Maryssa; Essalmani, Rachid; Poirier, Steve; Benjannet, Suzanne; Asselin, Marie-Claude; Roubtsova, Anna; Hamelin, Josée; Marcinkiewicz, Jadwiga; Chamberland, Ann; Guillemot, Johann; Mayer, Gaétan; Sisodia, Sangram S; Jacob, Yves; Prat, Annik; Seidah, Nabil G. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. The Journal Of Biological Chemistry. 2015;290(30):18609-20. PubMed |
| An, Dong; Wei, Xiaowei; Li, Hui; Gu, Hui; Huang, Tianchu; Zhao, Guifeng; Liu, Bo; Wang, Weilin; Chen, Lizhu; Ma, Wei; Zhang, Henan; Cao, Songying; Yuan, Zhengwei. Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. Scientific Reports. 2015;5:17559. PubMed |
| Haas, Mary E; Levenson, Amy E; Sun, Xiaowei; Liao, Wan-Hui; Rutkowski, Joseph M; de Ferranti, Sarah D; Schumacher, Valerie A; Scherer, Philipp E; Salant, David J; Biddinger, Sudha B. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation. 2016;134(1):61-72. PubMed |
| Ngo Sock, Emilienne Tudor; Mayer, Gaétan; Lavoie, Jean-Marc. Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats. Plos One. 11(7):e0159550. PubMed |
| Lintner, Nathanael G; McClure, Kim F; Petersen, Donna; Londregan, Allyn T; Piotrowski, David W; Wei, Liuqing; Xiao, Jun; Bolt, Michael; Loria, Paula M; Maguire, Bruce; Geoghegan, Kieran F; Huang, Austin; Rolph, Tim; Liras, Spiros; Doudna, Jennifer A; Dullea, Robert G; Cate, Jamie H D. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. Plos Biology. 2017;15(3):e2001882. PubMed |
| Xu, Yu-Xin; Redon, Valeska; Yu, Haojie; Querbes, William; Pirruccello, James; Liebow, Abigail; Deik, Amy; Trindade, Kevin; Wang, Xiao; Musunuru, Kiran; Clish, Clary B; Cowan, Chad; Fizgerald, Kevin; Rader, Daniel; Kathiresan, Sekar. Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis. 2018;268:196-206. PubMed |
| Yang, Sheng-Hua; Xu, Rui-Xia; Cui, Chuan-Jue; Wang, Yin; Du, Ying; Chen, Zhi-Guo; Yao, Yu-Hong; Ma, Chun-Yan; Zhu, Cheng-Gang; Guo, Yuan-Lin; Wu, Na-Qiong; Sun, Jing; Chen, Bu-Xing; Li, Jian-Jun. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovascular Diabetology. 2018;17(1):48. PubMed |
| Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Shahanawaz, Jiwani; Theus, Sue; Fan, Yubo; Deng, Xiaoyan; Zhou, Sichang; Mehta, Jawahar L. PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy. Cardiovascular Research. 2018;114(13):1738-1751. PubMed |
| Liu, Yan; Wang, Xiaona; Han, Jie; Liu, Lu; Jin, Ying; Jin, Liyuan; Ye, Ping. PCSK9 positively correlates with plasma sdLDL in community-dwelling population but not in diabetic participants after confounder adjustment. Medicine. 2019;98(14):e15062. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer. Archives Of Medical Science : Ams. 2019;15(3):559-569. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunization against PCSK9 in an experimental model of breast cancer. Archives Of Medical Science : Ams. 2019;15(3):570-579. PubMed |
| Momtazi-Borojeni, Amir Abbas; Jaafari, Mahmoud Reza; Badiee, Ali; Banach, Maciej; Sahebkar, Amirhossein. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. Bmc Medicine. 2019;17(1):223. PubMed |
| Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunisation against PCSK9 in mice bearing melanoma. Archives Of Medical Science : Ams. 16(1):189-199. PubMed |
| Low, Lauretta D; Lu, Liangjian; Chan, Chang-Yien; Chen, Jinmiao; Yang, Henry H; Yu, Hanry; Lee, Caroline G L; Ng, Kar-Hui; Yap, Hui-Kim. IL-13-driven alterations in hepatic cholesterol handling contributes to hypercholesterolemia in a rat model of minimal change disease. Clinical Science (London, England : 1979). 2020;134(2):225-237. PubMed |
| Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344. PubMed |
| St-Amand, Roxane; Ngo Sock, Émilienne T; Quinn, Samantha; Lavoie, Jean-Marc; St-Pierre, David H. Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats. Lipids In Health And Disease. 2020;19(1):192. PubMed |
| Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Zhou, Sichang; Kore, Rajshekhar A; Mu, Shengyu; Deng, Xiaoyan; Fan, Yubo; Mehta, Jawahar L. NLRP3 inflammasome via IL-1β regulates PCSK9 secretion. Theranostics. 10(16):7100-7110. PubMed |
