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MBL Life Sciences
| Product Specifications | |
| Application | ELISA |
| Documents & Links for CycLex® Rho-kinase Assay Kit | |
| Datasheet | CycLex® Rho-kinase Assay Kit Datasheet |
| Documents & Links for CycLex® Rho-kinase Assay Kit | |
| Datasheet | CycLex® Rho-kinase Assay Kit Datasheet |
| Citations for CycLex® Rho-kinase Assay Kit – 47 Found |
| Massaro, Marika; Zampolli, Antonella; Scoditti, Egeria; Carluccio, Maria Annunziata; Storelli, Carlo; Distante, Alessandro; De Caterina, Raffaele. Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. Cardiovascular Research. 2010;86(2):311-20. PubMed |
| Xu, Yue; Zhu, Xiuwen; Hahm, Heung Sik; Wei, Wanguo; Hao, Ergeng; Hayek, Alberto; Ding, Sheng. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2010;107(18):8129-34. PubMed |
| Torre, Carlos; Wang, Steven J; Xia, Weiliang; Bourguignon, Lilly Y W. Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling. Archives Of Otolaryngology--Head & Neck Surgery. 2010;136(5):493-501. PubMed |
| Lapointe, Tamia K; O'Connor, Pamela M; Jones, Nicola L; Menard, Daniel; Buret, Andre G. Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 during Helicobacter pylori infection. Cellular Microbiology. 2010;12(5):692-703. PubMed |
| Bivalacqua, Trinity J; Ross, Ashley E; Strong, Travis D; Gebska, Milena A; Musicki, Biljana; Champion, Hunter C; Burnett, Arthur L. Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice. Urology. 2010;76(2):510.e7-12. PubMed |
| Liu, Sijin; Li, Shitao; Du, Yuguo. Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK). Plos One. 2010;5(6):e11272. PubMed |
| Géraud, Cyrill; Schledzewski, Kai; Demory, Alexandra; Klein, Diana; Kaus, Miriam; Peyre, Francis; Sticht, Carsten; Evdokimov, Konstantin; Lu, Shun; Schmieder, Astrid; Goerdt, Sergij. Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology (Baltimore, Md.). 2010;52(1):313-26. PubMed |
| Fujimura, Masatake; Usuki, Fusako; Kawamura, Miwako; Izumo, Shuji. Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure. Toxicology And Applied Pharmacology. 2011;250(1):1-9. PubMed |
| Duong-Quy, S; Dao, P; Hua-Huy, T; Guilluy, C; Pacaud, P; Dinh-Xuan, A T. Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function. The European Respiratory Journal. 2011;37(2):349-55. PubMed |
| Gu, Xiaoxiao; Masters, Kristyn S. Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation. American Journal Of Physiology. Heart And Circulatory Physiology. 2011;300(2):H448-58. PubMed |
| Kirabo, Annet; Kearns, Patrick N; Jarajapu, Yagna P; Sasser, Jennifer M; Oh, Suk Paul; Grant, Maria B; Kasahara, Hideko; Cardounel, Arturo J; Baylis, Chris; Wagner, Kay-Uwe; Sayeski, Peter P. Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovascular Research. 2011;91(1):171-9. PubMed |
| Riganti, Chiara; Pinto, Hedwige; Bolli, Elisabetta; Belisario, Dimas C; Calogero, Raffaele A; Bosia, Amalia; Cavallo, Federica. Atorvastatin modulates anti-proliferative and pro-proliferative signals in Her2/neu-positive mammary cancer. Biochemical Pharmacology. 2011;82(9):1079-89. PubMed |
| Haidari, Mehran; Zhang, Wei; Ganjehei, Leila; Ali, Muzammil; Chen, Zhenping. Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agents. Plos One. 6(6):e21444. PubMed |
| Nölle, Anna; Zeug, Andre; van Bergeijk, Jeroen; Tönges, Lars; Gerhard, Ralf; Brinkmann, Hella; Al Rayes, Sarah; Hensel, Niko; Schill, Yvonne; Apkhazava, David; Jablonka, Sibylle; O'mer, Jana; Srivastav, Ratnesh Kumar; Baasner, Anne; Lingor, Paul; Wirth, Brunhilde; Ponimaskin, Evgeni; Niedenthal, Rainer; Grothe, Claudia; Claus, Peter. The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin. Human Molecular Genetics. 2011;20(24):4865-78. PubMed |
| Bagi, Zsolt; Feher, Attila; Cassuto, James; Akula, Komala; Labinskyy, Nazar; Kaley, Gabor; Koller, Akos. Increased availability of angiotensin AT 1 receptors leads to sustained arterial constriction to angiotensin II in diabetes - role for Rho-kinase activation. British Journal Of Pharmacology. 2011;163(5):1059-68. PubMed |
| Kobori, Hiroyuki; Ozawa, Yuri; Acres, Omar W; Miyata, Kayoko; Satou, Ryousuke. Rho-kinase/nuclear factor-κβ/angiotensinogen axis in angiotensin II-induced renal injury. Hypertension Research : Official Journal Of The Japanese Society Of Hypertension. 2011;34(8):976-9. PubMed |
| Shahin, Rand; Alqtaishat, Saja; Taha, Mutasem O. Elaborate ligand-based modeling reveal new submicromolar Rho kinase inhibitors. Journal Of Computer-Aided Molecular Design. 2012;26(2):249-66. PubMed |
| Morckel, Allison R; Lusic, Hrvoje; Farzana, Laila; Yoder, Jeffrey A; Deiters, Alexander; Nascone-Yoder, Nanette M. A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development (Cambridge, England). 2012;139(2):437-42. PubMed |
| Luke, Trevor; Maylor, Julie; Undem, Clark; Sylvester, J T; Shimoda, Larissa A. Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia. American Journal Of Physiology. Lung Cellular And Molecular Physiology. 2012;302(10):L1128-39. PubMed |
| Chang, Tzu-Ching; Chen, Yen-Chung; Yang, Ming-Hua; Chen, Chien-Hung; Hsing, En-Wei; Ko, Bor-Sheng; Liou, Jun-Yang; Wu, Kenneth K. Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner. Plos One. 2010;5(2):e9187. PubMed |
| Naraoka, Masato; Munakata, Akira; Matsuda, Naoya; Shimamura, Norihito; Ohkuma, Hiroki. Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. Translational Stroke Research. 2013;4(3):368-74. PubMed |
| Dush, Michael K; Nascone-Yoder, Nanette M. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development (Cambridge, England). 2013;140(7):1457-66. PubMed |
| Liang, Jia-lin; Yang, Guang-ming; Li, Tao; Liu, Liang-ming. Effects of interleukin-1β on vascular reactivity after lipopolysaccharide-induced endotoxic shock in rabbits and its relationship with PKC and Rho kinase. Journal Of Cardiovascular Pharmacology. 2013;62(1):84-9. PubMed |
| Riganti, Chiara; Castella, Barbara; Kopecka, Joanna; Campia, Ivana; Coscia, Marta; Pescarmona, Gianpiero; Bosia, Amalia; Ghigo, Dario; Massaia, Massimo. Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. Plos One. 8(4):e60975. PubMed |
| Takata, M; Tanaka, H; Kimura, M; Nagahara, Y; Tanaka, K; Kawasaki, K; Seto, M; Tsuruma, K; Shimazawa, M; Hara, H. Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis. British Journal Of Pharmacology. 2013;170(2):341-51. PubMed |
| Bourguignon, Lilly Y W; Wong, Gabriel; Xia, Weiliang; Man, Mao-Qiang; Holleran, Walter M; Elias, Peter M. Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. Journal Of Dermatological Science. 2013;72(1):32-44. PubMed |
| Bei, Yihua; Duong-Quy, Sy; Hua-Huy, Thong; Dao, Pierre; Le-Dong, Nhat-Nam; Dinh-Xuan, Anh Tuan. Activation of RhoA/Rho-kinase pathway accounts for pulmonary endothelial dysfunction in patients with chronic obstructive pulmonary disease. Physiological Reports. 2013;1(5):e00105. PubMed |
| Sari, A Nihal; Kacan, Meltem; Unsal, Demet; Sahan Firat, Seyhan; Kemal Buharalioglu, C; Vezir, Ozden; Korkmaz, Belma; Cuez, Tuba; Canacankatan, Necmiye; Sucu, Nehir; Ayaz, Lokman; Tamer Gumus, Lulufer; Gorur, Aysegul; Tunctan, Bahar. Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats. European Journal Of Pharmacology. 2014;723:234-45. PubMed |
| Kheirollah, Alireza; Nagayasu, Yuko; Ueda, Hiroshi; Yokoyama, Shinji; Michikawa, Makoto; Ito, Jin-ichi. Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes. Journal Of Neuroscience Research. 2014;92(4):455-63. PubMed |
| Li, Yan-Hua; Yu, Jie-Zhong; Liu, Chun-Yun; Zhang, Hui; Zhang, Hai-Fei; Yang, Wan-Fang; Li, Jun-Lian; Feng, Qian-Jin; Feng, Ling; Zhang, Guang-Xian; Xiao, Bao-Guo; Ma, Cun-Gen. Intranasal delivery of FSD-C10, a novel Rho kinase inhibitor, exhibits therapeutic potential in experimental autoimmune encephalomyelitis. Immunology. 2014;143(2):219-29. PubMed |
| Liu, Dong; Xiong, Renping; Chen, Xingyun; Li, Ping; Ning, Yalei; Peng, Yan; Zhao, Yan; Yang, Nan; Zhou, Yuanguo. The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways. Cellular Physiology And Biochemistry : International Journal Of Experimental Cellular Physiology, Biochemistry, And Pharmacology. 33(6):1654-62. PubMed |
| Pinzón-Daza, Martha L; Salaroglio, Iris C; Kopecka, Joanna; Garzòn, Ruth; Couraud, Pierre-Olivier; Ghigo, Dario; Riganti, Chiara. The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism. 2014;34(8):1258-69. PubMed |
| Chen, Zhengju; Zhang, Xu; Ying, Lei; Dou, Dou; Li, Yanhui; Bai, Yun; Liu, Juan; Liu, Limei; Feng, Han; Yu, Xiaoxing; Leung, Susan Wai-Sum; Vanhoutte, Paul M; Gao, Yuansheng. cIMP synthesized by sGC as a mediator of hypoxic contraction of coronary arteries. American Journal Of Physiology. Heart And Circulatory Physiology. 2014;307(3):H328-36. PubMed |
| Kwok, Willson; Clemens, Mark G. Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells. Shock (Augusta, Ga.). 2014;42(6):554-61. PubMed |
| Li, Hang; Wang, Donghua; Liu, Shuai; Sun, Changhai; Chen, Meizhu; Wang, Xinran; Chen, Ligong. Design, synthesis and evaluation of biological activity of novel fasudil analogues. Die Pharmazie. 2014;69(12):867-73. PubMed |
| Rigoni, Micol; Riganti, Chiara; Vitale, Candida; Griggio, Valentina; Campia, Ivana; Robino, Marta; Foglietta, Myriam; Castella, Barbara; Sciancalepore, Patrizia; Buondonno, Ilaria; Drandi, Daniela; Ladetto, Marco; Boccadoro, Mario; Massaia, Massimo; Coscia, Marta. Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells. Oncotarget. 2015;6(30):29833-46. PubMed |
| Gagliano-Jucá, Thiago; Napolitano, Mauro; Del Grossi Ferraz Carvalho, Fernanda; Campos, Rafael; Mónica, Fabíola Zakia; Claudino, Mário Angelo; Antunes, Edson; Lopes, Anibal Gil; De Nucci, Gilberto. Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle. Sexual Medicine. 2016;4(2):e113-23. PubMed |
| Hong, Jie; Li, Dan; Cao, Weibiao. Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells. Plos One. 11(2):e0149735. PubMed |
| Yuan, Tian-Yi; Chen, Yu-Cai; Zhang, Hui-Fang; Li, Li; Jiao, Xiao-Zhen; Xie, Ping; Fang, Lian-Hua; Du, Guan-Hua. DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes. Acta Pharmacologica Sinica. 2016;37(5):604-16. PubMed |
| Hannan, Johanna L; Matsui, Hotaka; Sopko, Nikolai A; Liu, Xiaopu; Weyne, Emmanuel; Albersen, Maarten; Watson, Joseph W; Hoke, Ahmet; Burnett, Arthur L; Bivalacqua, Trinity J. Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion. Scientific Reports. 2016;6:29416. PubMed |
| Zhang, Lei; Jiang, Guoliang; Zhao, Xueling; Gong, Yuekun. Dimethyloxalylglycine Promotes Bone Marrow Mesenchymal Stem Cell Osteogenesis via Rho/ROCK Signaling. Cellular Physiology And Biochemistry : International Journal Of Experimental Cellular Physiology, Biochemistry, And Pharmacology. 39(4):1391-403. PubMed |
| Takaoka, Miho; Ito, Shun; Miki, Yoshio; Nakanishi, Akira. FKBP51 regulates cell motility and invasion via RhoA signaling. Cancer Science. 2017;108(3):380-389. PubMed |
| Yao, Yangyang; Li, Renze; Liu, Xiaoyu; Yang, Feilong; Yang, Ying; Li, Xiaoyu; Shi, Xiang; Yuan, Tianyi; Fang, Lianhua; Du, Guanhua; Jiao, Xiaozhen; Xie, Ping. Discovery of Novel N-Substituted Prolinamido Indazoles as Potent Rho Kinase Inhibitors and Vasorelaxation Agents. Molecules (Basel, Switzerland). 2017;22(10) PubMed |
| Kashiwagi, Kenji; Ito, Sadahiro; Maeda, Shuichiro; Kato, Goro. A Ser75-to-Asp phospho-mimicking mutation in Src accelerates ageing-related loss of retinal ganglion cells in mice. Scientific Reports. 2017;7(1):16779. PubMed |
| Wang, Xin; Mao, Rongyan; Chen, Weiwei. FSD-C10 Shows Therapeutic Effects in Suppressing oxidized low-density lipoprotein (ox-LDL)-Induced Human Brain Microvascular Endothelial Cells Apoptosis via Rho-Associated Coiled-Coil Kinase (ROCK)/Mitogen-Activated Protein Kinase (MAPK) Signaling. Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research. 2018;24:5509-5516. PubMed |
| Kato, Goro. Nonphosphorylatable Src Ser75 Mutation Increases Ethanol Preference and Consumption in Mice. Eneuro. 2019;6(2) PubMed |
| Milosevic, Vladan; Kopecka, Joanna; Salaroglio, Iris C; Libener, Roberta; Napoli, Francesca; Izzo, Stefania; Orecchia, Sara; Ananthanarayanan, Preeta; Bironzo, Paolo; Grosso, Federica; Tabbò, Fabrizio; Comunanza, Valentina; Alexa-Stratulat, Teodora; Bussolino, Federico; Righi, Luisella; Novello, Silvia; Scagliotti, Giorgio V; Riganti, Chiara. Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5. International Journal Of Cancer. 2020;146(1):192-207. PubMed |
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MBL Life Sciences
| Product Specifications | |
| Application | ELISA |
| Documents & Links for CycLex® Rho-kinase Assay Kit | |
| Datasheet | CycLex® Rho-kinase Assay Kit Datasheet |
| Documents & Links for CycLex® Rho-kinase Assay Kit | |
| Datasheet | CycLex® Rho-kinase Assay Kit Datasheet |
| Citations for CycLex® Rho-kinase Assay Kit – 47 Found |
| Massaro, Marika; Zampolli, Antonella; Scoditti, Egeria; Carluccio, Maria Annunziata; Storelli, Carlo; Distante, Alessandro; De Caterina, Raffaele. Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. Cardiovascular Research. 2010;86(2):311-20. PubMed |
| Xu, Yue; Zhu, Xiuwen; Hahm, Heung Sik; Wei, Wanguo; Hao, Ergeng; Hayek, Alberto; Ding, Sheng. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2010;107(18):8129-34. PubMed |
| Torre, Carlos; Wang, Steven J; Xia, Weiliang; Bourguignon, Lilly Y W. Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling. Archives Of Otolaryngology--Head & Neck Surgery. 2010;136(5):493-501. PubMed |
| Lapointe, Tamia K; O'Connor, Pamela M; Jones, Nicola L; Menard, Daniel; Buret, Andre G. Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 during Helicobacter pylori infection. Cellular Microbiology. 2010;12(5):692-703. PubMed |
| Bivalacqua, Trinity J; Ross, Ashley E; Strong, Travis D; Gebska, Milena A; Musicki, Biljana; Champion, Hunter C; Burnett, Arthur L. Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice. Urology. 2010;76(2):510.e7-12. PubMed |
| Liu, Sijin; Li, Shitao; Du, Yuguo. Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK). Plos One. 2010;5(6):e11272. PubMed |
| Géraud, Cyrill; Schledzewski, Kai; Demory, Alexandra; Klein, Diana; Kaus, Miriam; Peyre, Francis; Sticht, Carsten; Evdokimov, Konstantin; Lu, Shun; Schmieder, Astrid; Goerdt, Sergij. Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology (Baltimore, Md.). 2010;52(1):313-26. PubMed |
| Fujimura, Masatake; Usuki, Fusako; Kawamura, Miwako; Izumo, Shuji. Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure. Toxicology And Applied Pharmacology. 2011;250(1):1-9. PubMed |
| Duong-Quy, S; Dao, P; Hua-Huy, T; Guilluy, C; Pacaud, P; Dinh-Xuan, A T. Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function. The European Respiratory Journal. 2011;37(2):349-55. PubMed |
| Gu, Xiaoxiao; Masters, Kristyn S. Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation. American Journal Of Physiology. Heart And Circulatory Physiology. 2011;300(2):H448-58. PubMed |
| Kirabo, Annet; Kearns, Patrick N; Jarajapu, Yagna P; Sasser, Jennifer M; Oh, Suk Paul; Grant, Maria B; Kasahara, Hideko; Cardounel, Arturo J; Baylis, Chris; Wagner, Kay-Uwe; Sayeski, Peter P. Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovascular Research. 2011;91(1):171-9. PubMed |
| Riganti, Chiara; Pinto, Hedwige; Bolli, Elisabetta; Belisario, Dimas C; Calogero, Raffaele A; Bosia, Amalia; Cavallo, Federica. Atorvastatin modulates anti-proliferative and pro-proliferative signals in Her2/neu-positive mammary cancer. Biochemical Pharmacology. 2011;82(9):1079-89. PubMed |
| Haidari, Mehran; Zhang, Wei; Ganjehei, Leila; Ali, Muzammil; Chen, Zhenping. Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agents. Plos One. 6(6):e21444. PubMed |
| Nölle, Anna; Zeug, Andre; van Bergeijk, Jeroen; Tönges, Lars; Gerhard, Ralf; Brinkmann, Hella; Al Rayes, Sarah; Hensel, Niko; Schill, Yvonne; Apkhazava, David; Jablonka, Sibylle; O'mer, Jana; Srivastav, Ratnesh Kumar; Baasner, Anne; Lingor, Paul; Wirth, Brunhilde; Ponimaskin, Evgeni; Niedenthal, Rainer; Grothe, Claudia; Claus, Peter. The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin. Human Molecular Genetics. 2011;20(24):4865-78. PubMed |
| Bagi, Zsolt; Feher, Attila; Cassuto, James; Akula, Komala; Labinskyy, Nazar; Kaley, Gabor; Koller, Akos. Increased availability of angiotensin AT 1 receptors leads to sustained arterial constriction to angiotensin II in diabetes - role for Rho-kinase activation. British Journal Of Pharmacology. 2011;163(5):1059-68. PubMed |
| Kobori, Hiroyuki; Ozawa, Yuri; Acres, Omar W; Miyata, Kayoko; Satou, Ryousuke. Rho-kinase/nuclear factor-κβ/angiotensinogen axis in angiotensin II-induced renal injury. Hypertension Research : Official Journal Of The Japanese Society Of Hypertension. 2011;34(8):976-9. PubMed |
| Shahin, Rand; Alqtaishat, Saja; Taha, Mutasem O. Elaborate ligand-based modeling reveal new submicromolar Rho kinase inhibitors. Journal Of Computer-Aided Molecular Design. 2012;26(2):249-66. PubMed |
| Morckel, Allison R; Lusic, Hrvoje; Farzana, Laila; Yoder, Jeffrey A; Deiters, Alexander; Nascone-Yoder, Nanette M. A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development (Cambridge, England). 2012;139(2):437-42. PubMed |
| Luke, Trevor; Maylor, Julie; Undem, Clark; Sylvester, J T; Shimoda, Larissa A. Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia. American Journal Of Physiology. Lung Cellular And Molecular Physiology. 2012;302(10):L1128-39. PubMed |
| Chang, Tzu-Ching; Chen, Yen-Chung; Yang, Ming-Hua; Chen, Chien-Hung; Hsing, En-Wei; Ko, Bor-Sheng; Liou, Jun-Yang; Wu, Kenneth K. Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner. Plos One. 2010;5(2):e9187. PubMed |
| Naraoka, Masato; Munakata, Akira; Matsuda, Naoya; Shimamura, Norihito; Ohkuma, Hiroki. Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. Translational Stroke Research. 2013;4(3):368-74. PubMed |
| Dush, Michael K; Nascone-Yoder, Nanette M. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development (Cambridge, England). 2013;140(7):1457-66. PubMed |
| Liang, Jia-lin; Yang, Guang-ming; Li, Tao; Liu, Liang-ming. Effects of interleukin-1β on vascular reactivity after lipopolysaccharide-induced endotoxic shock in rabbits and its relationship with PKC and Rho kinase. Journal Of Cardiovascular Pharmacology. 2013;62(1):84-9. PubMed |
| Riganti, Chiara; Castella, Barbara; Kopecka, Joanna; Campia, Ivana; Coscia, Marta; Pescarmona, Gianpiero; Bosia, Amalia; Ghigo, Dario; Massaia, Massimo. Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. Plos One. 8(4):e60975. PubMed |
| Takata, M; Tanaka, H; Kimura, M; Nagahara, Y; Tanaka, K; Kawasaki, K; Seto, M; Tsuruma, K; Shimazawa, M; Hara, H. Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis. British Journal Of Pharmacology. 2013;170(2):341-51. PubMed |
| Bourguignon, Lilly Y W; Wong, Gabriel; Xia, Weiliang; Man, Mao-Qiang; Holleran, Walter M; Elias, Peter M. Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. Journal Of Dermatological Science. 2013;72(1):32-44. PubMed |
| Bei, Yihua; Duong-Quy, Sy; Hua-Huy, Thong; Dao, Pierre; Le-Dong, Nhat-Nam; Dinh-Xuan, Anh Tuan. Activation of RhoA/Rho-kinase pathway accounts for pulmonary endothelial dysfunction in patients with chronic obstructive pulmonary disease. Physiological Reports. 2013;1(5):e00105. PubMed |
| Sari, A Nihal; Kacan, Meltem; Unsal, Demet; Sahan Firat, Seyhan; Kemal Buharalioglu, C; Vezir, Ozden; Korkmaz, Belma; Cuez, Tuba; Canacankatan, Necmiye; Sucu, Nehir; Ayaz, Lokman; Tamer Gumus, Lulufer; Gorur, Aysegul; Tunctan, Bahar. Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats. European Journal Of Pharmacology. 2014;723:234-45. PubMed |
| Kheirollah, Alireza; Nagayasu, Yuko; Ueda, Hiroshi; Yokoyama, Shinji; Michikawa, Makoto; Ito, Jin-ichi. Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes. Journal Of Neuroscience Research. 2014;92(4):455-63. PubMed |
| Li, Yan-Hua; Yu, Jie-Zhong; Liu, Chun-Yun; Zhang, Hui; Zhang, Hai-Fei; Yang, Wan-Fang; Li, Jun-Lian; Feng, Qian-Jin; Feng, Ling; Zhang, Guang-Xian; Xiao, Bao-Guo; Ma, Cun-Gen. Intranasal delivery of FSD-C10, a novel Rho kinase inhibitor, exhibits therapeutic potential in experimental autoimmune encephalomyelitis. Immunology. 2014;143(2):219-29. PubMed |
| Liu, Dong; Xiong, Renping; Chen, Xingyun; Li, Ping; Ning, Yalei; Peng, Yan; Zhao, Yan; Yang, Nan; Zhou, Yuanguo. The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways. Cellular Physiology And Biochemistry : International Journal Of Experimental Cellular Physiology, Biochemistry, And Pharmacology. 33(6):1654-62. PubMed |
| Pinzón-Daza, Martha L; Salaroglio, Iris C; Kopecka, Joanna; Garzòn, Ruth; Couraud, Pierre-Olivier; Ghigo, Dario; Riganti, Chiara. The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism. 2014;34(8):1258-69. PubMed |
| Chen, Zhengju; Zhang, Xu; Ying, Lei; Dou, Dou; Li, Yanhui; Bai, Yun; Liu, Juan; Liu, Limei; Feng, Han; Yu, Xiaoxing; Leung, Susan Wai-Sum; Vanhoutte, Paul M; Gao, Yuansheng. cIMP synthesized by sGC as a mediator of hypoxic contraction of coronary arteries. American Journal Of Physiology. Heart And Circulatory Physiology. 2014;307(3):H328-36. PubMed |
| Kwok, Willson; Clemens, Mark G. Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells. Shock (Augusta, Ga.). 2014;42(6):554-61. PubMed |
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