Product Description
Anti-mouse CD8 clone choice is critical when mouse MHC I tetramers, as some clones, including 53-6.7, lead to high background staining of all CD8+ T cells, rather than the antigen-specific ones.
For best results, clone KT15 in FITC (MBL-K0227-4) is recommended. Additional information can be found in the datasheet that accompanies mouse class I tetramers, as well as the following reference containing a protocol for performing a cross titration series for optimization: Current Protocols in Immunology, MHC-Peptide tetramers to Visualize Antigen-Specific T Cells, Section 17.3.23-24, Supplement 154
| Product Specifications |
| Application |
FC |
| Reactivity |
Mouse |
| Conjugation |
PE |
| Immunogen |
RSV M2 82-90 |
| Peptide Sequence |
SYIGSINNI |
| Class |
Class I |
| Sequence Location |
82-90 |
| MHC Allele |
H-2Kd |
| Citations for iTAg Tetramer/PE - H-2 Kd RSV M2 (SYIGSINNI) – 1 Found |
| Cheemarla, Nagarjuna R; Uche, Ifeanyi K; McBride, Kaitlin; Naidu, Shan; Guerrero-Plata, Antonieta. In utero tobacco smoke exposure alters lung inflammation, viral clearance, and CD8(+) T-cell responses in neonatal mice infected with respiratory syncytial virus. American Journal Of Physiology. Lung Cellular And Molecular Physiology. 2019;317(2):L212-L221. PubMed |
