Academic users: Please submit a completed MTA form with your order to orders@cosmobiousa.com.
Commercial users: Please contact us at orders@cosmobiousa.com before placing an order. A license agreement with MBL International will need to be completed for ordering.

Product Description

Mitophagy detection vectors are designed for the co-expression of MT-mKeima-Red. (CoralHue®Mitochondria-targeted monomeric Keima-Red) gene and mouse Parkin (mPark2) gene from the internal ribosome entry site (IRES), as part of a bicistronic transcript in mammalian cells. Keima-Red has been cloned from Montipara sp. A monomeric version of CoralHue®Keima-Red (mKeima-Red) displays a bimodal excitation spectrum with peaks at 440 and 586nm in neutral and acidic solutions, respectively, and an emission maximum at 620nm. Mitochondrial targeting of mKeima-Red is achieved by introducing a mitochondrial signal sequence at the N-terminus of mKeima-Red.

Academic users: Please submit a completed MTA form with your order to orders@cosmobiousa.com.
Commercial users: Please contact us at orders@cosmobiousa.com before placing an order. A license agreement with MBL International will need to be completed for ordering.

Product Description

Mitophagy detection vectors are designed for the co-expression of MT-mKeima-Red. (CoralHue®Mitochondria-targeted monomeric Keima-Red) gene and mouse Parkin (mPark2) gene from the internal ribosome entry site (IRES), as part of a bicistronic transcript in mammalian cells. Keima-Red has been cloned from Montipara sp. A monomeric version of CoralHue®Keima-Red (mKeima-Red) displays a bimodal excitation spectrum with peaks at 440 and 586nm in neutral and acidic solutions, respectively, and an emission maximum at 620nm. Mitochondrial targeting of mKeima-Red is achieved by introducing a mitochondrial signal sequence at the N-terminus of mKeima-Red.